A prospective observational study on maternal thyroid-stimulating hormone and its impact on maternal and perinatal outcome

Background: Numerous hormonal changes and metabolic demands occur during pregnancy, resulting in complex maternal thyroid function. Thyroid disorder is the second most common endocrine found pregnancy next to diabetes group. It affects 1–2% of women reproductive age. Overt hypothyroidism complicates 0.3–0.5% pregnancies. The incidence subclinical pregnant about 2–3%. Hyperthyroidism present 0.1–0.4%. Aims Objectives: aim study was assess function test its effect on fetal outcomes. Materials Methods: A prospective observational conducted Department Obstetrics Gynaecology at Dhanalakshmi Srinivasan Medical College Hospital, Tamil Nadu over a period 1 year February 2019 January 2020. screen for disorders based their serum stimulating hormone (TSH) first antenatal visit impact perinatal Results: In our study, overall abnormality be 5.5%. statistically significant (P<0.001). Subclinical hypothyroid as major population (significant P<0.002). overt hyperthyroidism: 0.5%, hypothyroidism: 3.5%, primary 1.5% found. More than 54% had no high-risk factors were have disorder. complications with analyzed. One woman hypothyroidism, one developed mild preeclampsia. preterm labor 32 weeks gestational Maternal less inadequately treated patients normal these complications. birth weight babies, <2.5 kg 18.2%, 2.5–3 63.6%, >3 18.2%. Perinatal outcomes terms preterm, intrauterine growth restriction, low birthweight, distress. Conclusion: All irrespective risks or high should screened TSH booking prevent close monitoring effective treatment could provided them.